Your search
Results 6 resources
-
An evidence-based guide to current understanding of lipedema, its causes and possible treatments, addressing what is known through human studies, what is unknown and needs investigating, and what is likely to emerge. Lipedema (or lipoedema) is a chronic lymphatic disorder in which abnormal levels of fat build up disproportionately in certain areas of the body, most commonly the hips, bottom and legs. Almost exclusively affecting women, who may seek help for years only to be met with ongoing anti-fat stereotyping, its significant life-changing impact has only recently been recognized, clinically and in terms of research funding. Even though research is now accelerating, there is still much left to be discovered. This book brings together the current knowns, unknowns and conjectures as a comprehensive resource for researchers, clinicians and patients seeking a roadmap to potentially improving the lives of up to 17 million women in the US and 350 million worldwide.
-
Background: Our aim is to propose a framework for the development of a research case definition of lipedema, based on current available literature and those observations that can be applied to future lipedema research with the intent to standardize and strengthen the scientific evidence base. Methods and Results: We conducted a narrative review of the literature, and identified consensus characteristics and disputed characteristics that could be included in a research case definition of lipedema. After considering the strength of the evidence and how each characteristic might be measured in a research study, we recommended an approach for the development of a research case definition of lipedema that would be based on consideration of five agreed-upon characteristics, and five disputed, or less substantiated, characteristics as additional evidence to enhance specificity. Conclusions: We present a case definition framework for lipedema drawn from the scientific literature that can be applied to future studies on lipedema. Utilizing this framework should help to increase the sensitivity and specificity of case definition and provide an opportunity for meta-analysis of clinical studies and facilitate future research intercomparisons.
Explore
Resource type
- Book (2)
- Journal Article (4)
Publication year
- Between 2000 and 2026 (5)
- Unknown (1)