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Key signaling networks are dysregulated in patients with the adipose tissue disorder, lipedema
Resource type
Authors/contributors
- Ishaq, Musarat (Author)
- Bandara, Nadeeka (Author)
- Morgan, Steven (Author)
- Nowell, Cameron (Author)
- Mehdi, Ahmad M. (Author)
- Lyu, Ruqian (Author)
- McCarthy, Davis (Author)
- Anderson, Dovile (Author)
- Creek, Darren J. (Author)
- Achen, Marc G. (Author)
- Shayan, Ramin (Author)
- Karnezis, Tara (Author)
Title
Key signaling networks are dysregulated in patients with the adipose tissue disorder, lipedema
Abstract
Lipedema, a poorly understood chronic disease of adipose hyper-deposition, is often mistaken for obesity and causes significant impairment to mobility and quality-of-life. To identify molecular mechanisms underpinning lipedema, we employed comprehensive omics-based comparative analyses of whole tissue, adipocyte precursors (adipose-derived stem cells (ADSCs)), and adipocytes from patients with or without lipedema.
Publication
International Journal of Obesity
Pages
1-13
Date
2021-11-11
Journal Abbr
Int J Obes
Language
en
ISSN
1476-5497
Accessed
11/16/21, 2:22 PM
Library Catalog
Rights
2021 The Author(s)
Citation
Ishaq, M., Bandara, N., Morgan, S., Nowell, C., Mehdi, A. M., Lyu, R., McCarthy, D., Anderson, D., Creek, D. J., Achen, M. G., Shayan, R., & Karnezis, T. (2021). Key signaling networks are dysregulated in patients with the adipose tissue disorder, lipedema. International Journal of Obesity, 1–13. https://doi.org/10.1038/s41366-021-01002-1
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