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Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium

Resource type
Authors/contributors
Title
Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium
Abstract
Enhancing our understanding of lymphatic anatomy from the microscopic to the anatomical scale is essential to discern how the structure and function of the lymphatic system interacts with different tissues and organs within the body and contributes to health and disease. The knowledge of molecular aspects of the lymphatic network is fundamental to understand the mechanisms of disease progression and prevention. Recent advances in mapping components of the lymphatic system using state of the art single cell technologies, the identification of novel biomarkers, new clinical imaging efforts, and computational tools which attempt to identify connections between these diverse technologies hold the potential to catalyze new strategies to address lymphatic diseases such as lymphedema and lipedema. This manuscript summarizes current knowledge of the lymphatic system and identifies prevailing challenges and opportunities to advance the field of lymphatic research as discussed by the experts in the workshop.
Publication
Frontiers in Physiology
Volume
14
Pages
1099403
Date
2023
Journal Abbr
Front Physiol
Language
eng
ISSN
1664-042X
Short Title
Mapping the lymphatic system across body scales and expertise domains
Library Catalog
PubMed
Citation
Singhal, D., Börner, K., Chaikof, E. L., Detmar, M., Hollmén, M., Iliff, J. J., Itkin, M., Makinen, T., Oliver, G., Padera, T. P., Quardokus, E. M., Radtke, A. J., Suami, H., Weber, G. M., Rovira, I. I., Muratoglu, S. C., & Galis, Z. S. (2023). Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium. Frontiers in Physiology, 14, 1099403. https://doi.org/10.3389/fphys.2023.1099403
Publication